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SMILES: O=C(Nc1ccncc1)c1ccc2c(Nc3ccccc3NC2=O)c1

InChI Key: InChIKey=NZRFZJAHSHAEAC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299238   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))		BDBM50299238
PNG
(CHEMBL578437 | Methyl 11-Oxo-N-(pyridin-4-yl)-10,1...)
Show SMILES O=C(Nc1ccncc1)c1ccc2c(Nc3ccccc3NC2=O)c1
Show InChI InChI=1S/C19H14N4O2/c24-18(21-13-7-9-20-10-8-13)12-5-6-14-17(11-12)22-15-3-1-2-4-16(15)23-19(14)25/h1-11,22H,(H,23,25)(H,20,21,24)
PDB
MMDB

KEGG

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antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
 295n/an/an/an/an/an/an/an/a



University of Sharjah

Curated by ChEMBL


Assay Description
Inhibition of human recombinant BACE1 by FRET assay

J Med Chem 52: 6484-8 (2009)


Article DOI: 10.1021/jm9008482
BindingDB Entry DOI: 10.7270/Q2765FC2
More data for this
Ligand-Target Pair