BDBM50299240 3-(5-(Pyridin-4-yl)-1H-imidazol-2-yl)-5H dibenzo[b,e][1,4]-diazepin-11(10H)-one::CHEMBL575567

SMILES: O=C(Nc1nc(c[nH]1)-c1ccncc1)c1ccc2c(Nc3ccccc3NC2=O)c1

InChI Key: InChIKey=RNIRGRORYKVWBR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50299240 (3-(5-(Pyridin-4-yl)-1H-imidazol-2-yl)-5H dibenzo[b...) Show SMILES O=C(Nc1nc(c[nH]1)-c1ccncc1)c1ccc2c(Nc3ccccc3NC2=O)c1 Show InChI InChI=1S/C22H16N6O2/c29-20(28-22-24-12-19(27-22)13-7-9-23-10-8-13)14-5-6-15-18(11-14)25-16-3-1-2-4-17(16)26-21(15)30/h1-12,25H,(H,26,30)(H2,24,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	348	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant BACE1 by FRET assay				J Med Chem 52: 6484-8 (2009) Article DOI: 10.1021/jm9008482 BindingDB Entry DOI: 10.7270/Q2765FC2
					More data for this Ligand-Target Pair