BDBM50299245 7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde::CHEMBL584195::US8481586, 16

SMILES: Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1

InChI Key: InChIKey=KUIXBLRMWNOGNN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of Pim-1				J Med Chem 52: 6369-81 (2009) Article DOI: 10.1021/jm901018f BindingDB Entry DOI: 10.7270/Q23F4PPS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of Pim-3				J Med Chem 52: 6369-81 (2009) Article DOI: 10.1021/jm901018f BindingDB Entry DOI: 10.7270/Q23F4PPS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50299245 (7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1 Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II US Patent					Assay Description Inhibition assay using PIM-1, PIM-2 and PIM-3.				US Patent US8481586 (2013) BindingDB Entry DOI: 10.7270/Q2ZC81GT
					More data for this Ligand-Target Pair