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SMILES: C(Cc1ccccc1)Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1

InChI Key: InChIKey=AWMGQCCTIZRQSA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299362   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50299362
PNG
(CHEMBL575798 | N2-phenethyl-6-(piperazin-1-yl)-N4-...)
Show SMILES C(Cc1ccccc1)Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1
Show InChI InChI=1S/C20H24N8/c1-2-4-16(5-3-1)6-11-23-18-25-19(24-17-7-9-21-10-8-17)27-20(26-18)28-14-12-22-13-15-28/h1-5,7-10,22H,6,11-15H2,(H2,21,23,24,25,26,27)
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Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 19: 6027-31 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.046
BindingDB Entry DOI: 10.7270/Q2668D7P
More data for this
Ligand-Target Pair