BDBM50299391 4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N,N-diethylbenzamide::CHEMBL573757
SMILES: CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(Cc2ccccc2)CC1)c1cccc(N)c1
InChI Key: InChIKey=KVPYTQSFSGJMNO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50299391 (4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montr£al Curated by ChEMBL | Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor | Bioorg Med Chem Lett 19: 5999-6003 (2009) Article DOI: 10.1016/j.bmcl.2009.09.068 BindingDB Entry DOI: 10.7270/Q2XP7512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50299391 (4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montr£al Curated by ChEMBL | Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor | Bioorg Med Chem Lett 19: 5999-6003 (2009) Article DOI: 10.1016/j.bmcl.2009.09.068 BindingDB Entry DOI: 10.7270/Q2XP7512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50299391 (4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montr£al Curated by ChEMBL | Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor | Bioorg Med Chem Lett 19: 5999-6003 (2009) Article DOI: 10.1016/j.bmcl.2009.09.068 BindingDB Entry DOI: 10.7270/Q2XP7512 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50299391 (4-((3-aminophenyl)(1-benzylpiperidin-4-yl)amino)-N...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
AstraZeneca R&D Montr£al Curated by ChEMBL | Assay Description Agonist activity at human delta opioid receptor by GTP[gamma]35S binding assay | Bioorg Med Chem Lett 19: 5999-6003 (2009) Article DOI: 10.1016/j.bmcl.2009.09.068 BindingDB Entry DOI: 10.7270/Q2XP7512 | |||||||||||
More data for this Ligand-Target Pair |