BDBM50299475 CHEMBL566530::Ethyl 2-amino-5-(2-chlorophenyl)-4-methylthiophene-3-carboxylate

SMILES: CCOC(=O)c1c(N)sc(c1C)-c1ccccc1Cl

InChI Key: InChIKey=ZEPRJTIROOGJSN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50299475 (CHEMBL566530 | Ethyl 2-amino-5-(2-chlorophenyl)-4-...) Show SMILES CCOC(=O)c1c(N)sc(c1C)-c1ccccc1Cl Show InChI InChI=1S/C14H14ClNO2S/c1-3-18-14(17)11-8(2)12(19-13(11)16)9-6-4-5-7-10(9)15/h4-7H,3,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Leipzig Curated by ChEMBL					Assay Description Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx ...				Eur J Med Chem 45: 69-77 (2010) Article DOI: 10.1016/j.ejmech.2009.09.025 BindingDB Entry DOI: 10.7270/Q28S4QVF
					More data for this Ligand-Target Pair