Found 5 hits for monomerid = 50299569 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50299569
(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)Show SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C21H30N2O5/c1-15-12-23(13-16(2)27-15)21(24)14-26-22-11-17-8-9-19(25-3)20(10-17)28-18-6-4-5-7-18/h8-11,15-16,18H,4-7,12-14H2,1-3H3/b22-11+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Genoa
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PDE4D3 expressed in baculoviral system |
J Med Chem 57: 7061-72 (2014)
Article DOI: 10.1021/jm500855w
BindingDB Entry DOI: 10.7270/Q23N251C |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50299569
(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)Show SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C21H30N2O5/c1-15-12-23(13-16(2)27-15)21(24)14-26-22-11-17-8-9-19(25-3)20(10-17)28-18-6-4-5-7-18/h8-11,15-16,18H,4-7,12-14H2,1-3H3/b22-11+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Genoa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE4D3 expressed in baculovirus system by IMAP assay |
J Med Chem 52: 6546-57 (2009)
Article DOI: 10.1021/jm900977c
BindingDB Entry DOI: 10.7270/Q2N879VV |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50299569
(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)Show SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C21H30N2O5/c1-15-12-23(13-16(2)27-15)21(24)14-26-22-11-17-8-9-19(25-3)20(10-17)28-18-6-4-5-7-18/h8-11,15-16,18H,4-7,12-14H2,1-3H3/b22-11+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50299569
(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)Show SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C21H30N2O5/c1-15-12-23(13-16(2)27-15)21(24)14-26-22-11-17-8-9-19(25-3)20(10-17)28-18-6-4-5-7-18/h8-11,15-16,18H,4-7,12-14H2,1-3H3/b22-11+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50299569
(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)Show SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C21H30N2O5/c1-15-12-23(13-16(2)27-15)21(24)14-26-22-11-17-8-9-19(25-3)20(10-17)28-18-6-4-5-7-18/h8-11,15-16,18H,4-7,12-14H2,1-3H3/b22-11+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Genoa
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE4D expressed in Sf9 cells |
J Med Chem 52: 6546-57 (2009)
Article DOI: 10.1021/jm900977c
BindingDB Entry DOI: 10.7270/Q2N879VV |
More data for this
Ligand-Target Pair | |
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