BDBM50299571 3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-chloro-3-(2,6-dimethylmorpholin-4-yl)propyl]-oxime::CHEMBL570355

SMILES: COc1ccc(\C=N\OCC(Cl)CN2CC(C)OC(C)C2)cc1OC1CCCC1

InChI Key: InChIKey=QLALEKANVSJGOR-BHGWPJFGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50299571 (3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-chlo...) Show SMILES COc1ccc(\C=N\OCC(Cl)CN2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C22H33ClN2O4/c1-16-12-25(13-17(2)28-16)14-19(23)15-27-24-11-18-8-9-21(26-3)22(10-18)29-20-6-4-5-7-20/h8-11,16-17,19-20H,4-7,12-15H2,1-3H3/b24-11+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D expressed in Sf9 cells				J Med Chem 52: 6546-57 (2009) Article DOI: 10.1021/jm900977c BindingDB Entry DOI: 10.7270/Q2N879VV
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50299571 (3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-chlo...) Show SMILES COc1ccc(\C=N\OCC(Cl)CN2CC(C)OC(C)C2)cc1OC1CCCC1 Show InChI InChI=1S/C22H33ClN2O4/c1-16-12-25(13-17(2)28-16)14-19(23)15-27-24-11-18-8-9-21(26-3)22(10-18)29-20-6-4-5-7-20/h8-11,16-17,19-20H,4-7,12-15H2,1-3H3/b24-11+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D3 expressed in baculovirus system by IMAP assay				J Med Chem 52: 6546-57 (2009) Article DOI: 10.1021/jm900977c BindingDB Entry DOI: 10.7270/Q2N879VV
					More data for this Ligand-Target Pair