BDBM50299588 1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-o-tolylpiperidine-4-carboxamide::CHEMBL578599

SMILES: Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3ccccc3C)c12

InChI Key: InChIKey=RFPNUIOUJIEGLY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50299588 (1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-o-t...) Show SMILES Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3ccccc3C)c12 Show InChI InChI=1S/C20H23N5O/c1-13-5-3-4-6-16(13)24-20(26)15-7-9-25(10-8-15)19-17-14(2)11-21-18(17)22-12-23-19/h3-6,11-12,15H,7-10H2,1-2H3,(H,24,26)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting				J Med Chem 52: 6515-8 (2009) Article DOI: 10.1021/jm901226j BindingDB Entry DOI: 10.7270/Q2HH6K4J
					More data for this Ligand-Target Pair