BDBM50299593 1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-(3-phenoxyphenyl)piperidine-4-carboxamide::CHEMBL570109

SMILES: Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3cccc(Oc4ccccc4)c3)c12

InChI Key: InChIKey=SLUWFPJROQKLET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50299593 (1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N-(3-...) Show SMILES Cc1c[nH]c2ncnc(N3CCC(CC3)C(=O)Nc3cccc(Oc4ccccc4)c3)c12 Show InChI InChI=1S/C25H25N5O2/c1-17-15-26-23-22(17)24(28-16-27-23)30-12-10-18(11-13-30)25(31)29-19-6-5-9-21(14-19)32-20-7-3-2-4-8-20/h2-9,14-16,18H,10-13H2,1H3,(H,29,31)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting				J Med Chem 52: 6515-8 (2009) Article DOI: 10.1021/jm901226j BindingDB Entry DOI: 10.7270/Q2HH6K4J
					More data for this Ligand-Target Pair