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SMILES: C[C@H]1CN(CCN1C(NS(C)(=O)=O)=Nc1cccc(Br)c1)c1ncnc2[nH]cc(C)c12

InChI Key: InChIKey=ZZABGZFZUJBLLS-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299610   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
LIM domain kinase 2


(Homo sapiens (Human))		BDBM50299610
PNG
((S)-N-(3-bromophenyl)-2-methyl-4-(5-methyl-7H-pyrr...)
Show SMILES C[C@H]1CN(CCN1C(NS(C)(=O)=O)=Nc1cccc(Br)c1)c1ncnc2[nH]cc(C)c12 |r,w:13.14|
Show InChI InChI=1S/C20H24BrN7O2S/c1-13-10-22-18-17(13)19(24-12-23-18)27-7-8-28(14(2)11-27)20(26-31(3,29)30)25-16-6-4-5-15(21)9-16/h4-6,9-10,12,14H,7-8,11H2,1-3H3,(H,25,26)(H,22,23,24)/t14-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 6.80n/an/an/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting

J Med Chem 52: 6515-8 (2009)


Article DOI: 10.1021/jm901226j
BindingDB Entry DOI: 10.7270/Q2HH6K4J
More data for this
Ligand-Target Pair