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SMILES: CC(C)[C@@H](N[C@H](C)c1ccccc1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=QVYKGSXEOYTESD-IIBYNOLFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299678   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50299678
PNG
((1R)-2-methyl-N-((1R)-1-phenylethyl)-1-(1-(4-(trif...)
Show SMILES CC(C)[C@@H](N[C@H](C)c1ccccc1)c1ccn(n1)-c1ccc(cc1)C(F)(F)F |r|
Show InChI InChI=1S/C22H24F3N3/c1-15(2)21(26-16(3)17-7-5-4-6-8-17)20-13-14-28(27-20)19-11-9-18(10-12-19)22(23,24)25/h4-16,21,26H,1-3H3/t16-,21-/m1/s1
PDB

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 2.34E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assay

J Med Chem 52: 6535-8 (2009)


Article DOI: 10.1021/jm9012278
BindingDB Entry DOI: 10.7270/Q28052PS
More data for this
Ligand-Target Pair