BDBM50300052 5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one::CHEMBL572923

SMILES: Cc1ccc(CN2c3ccccc3-c3[nH]c4ccccc4c3CC2=O)cc1

InChI Key: InChIKey=PSPWZGBZRWYJLW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malate dehydrogenase, mitochondrial (Homo sapiens (Human))	BDBM50300052 (5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...) Show SMILES Cc1ccc(CN2c3ccccc3-c3[nH]c4ccccc4c3CC2=O)cc1 Show InChI InChI=1S/C24H20N2O/c1-16-10-12-17(13-11-16)15-26-22-9-5-3-7-19(22)24-20(14-23(26)27)18-6-2-4-8-21(18)25-24/h2-13,25H,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of mitochondrial malate dehydrogenase by spectrophotometry				Eur J Med Chem 45: 335-42 (2010) Article DOI: 10.1016/j.ejmech.2009.10.018 BindingDB Entry DOI: 10.7270/Q26W9C1V
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50300052 (5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...) Show SMILES Cc1ccc(CN2c3ccccc3-c3[nH]c4ccccc4c3CC2=O)cc1 Show InChI InChI=1S/C24H20N2O/c1-16-10-12-17(13-11-16)15-26-22-9-5-3-7-19(22)24-20(14-23(26)27)18-6-2-4-8-21(18)25-24/h2-13,25H,14-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of GSK3-beta				Eur J Med Chem 45: 335-42 (2010) Article DOI: 10.1016/j.ejmech.2009.10.018 BindingDB Entry DOI: 10.7270/Q26W9C1V
					More data for this Ligand-Target Pair
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human))	BDBM50300052 (5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...) Show SMILES Cc1ccc(CN2c3ccccc3-c3[nH]c4ccccc4c3CC2=O)cc1 Show InChI InChI=1S/C24H20N2O/c1-16-10-12-17(13-11-16)15-26-22-9-5-3-7-19(22)24-20(14-23(26)27)18-6-2-4-8-21(18)25-24/h2-13,25H,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B				Eur J Med Chem 45: 335-42 (2010) Article DOI: 10.1016/j.ejmech.2009.10.018 BindingDB Entry DOI: 10.7270/Q26W9C1V
					More data for this Ligand-Target Pair