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BDBM50300340 1-Biphenyl-3-ylmaleimide::CHEMBL567622::cid_930984

SMILES: O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1

InChI Key: InChIKey=QQAJYNGNBJIZPR-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50300340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
60S ribosomal protein L19-A


(Saccharomyces cerevisiae)
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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CHEMBL
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n/an/an/an/a 2.70E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2JQ0ZGP
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
PDB

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Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



Louvain Drug Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]ethanolamine from human recombinant FAAH by liquid scintillation counting


J Med Chem 52: 7410-20 (2009)


Article DOI: 10.1021/jm900461w
BindingDB Entry DOI: 10.7270/Q2TM7B59
More data for this
Ligand-Target Pair
Endothelial PAS domain-containing protein 1


(Homo sapiens (Human))
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
PDB
MMDB

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n/an/a 8.09E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2WS8RVZ
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
PDB
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Article
PubMed
n/an/a 2.34E+3n/an/an/an/an/an/a



Louvain Drug Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]2-OG from human MGL by liquid scintillation counting


J Med Chem 52: 7410-20 (2009)


Article DOI: 10.1021/jm900461w
BindingDB Entry DOI: 10.7270/Q2TM7B59
More data for this
Ligand-Target Pair
Vacuolar aminopeptidase 1


(Saccharomyces cerevisiae)
BDBM50300340
PNG
(1-Biphenyl-3-ylmaleimide | CHEMBL567622 | cid_9309...)
Show SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1 |c:2|
Show InChI InChI=1S/C16H11NO2/c18-15-9-10-16(19)17(15)14-8-4-7-13(11-14)12-5-2-1-3-6-12/h1-11H
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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PCBioAssay
n/an/an/an/a 385n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair