BDBM50300454 CHEMBL574378::N-hydroxy-2,2-bis(4-(methylsulfonamido)phenyl)acetamide

SMILES: CS(=O)(=O)Nc1ccc(cc1)C(C(=O)NO)c1ccc(NS(C)(=O)=O)cc1

InChI Key: InChIKey=NDCGISZPOIMWEF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 5 (Homo sapiens (Human))	BDBM50300454 (CHEMBL574378 | N-hydroxy-2,2-bis(4-(methylsulfonam...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(C(=O)NO)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C16H19N3O6S2/c1-26(22,23)18-13-7-3-11(4-8-13)15(16(20)17-21)12-5-9-14(10-6-12)19-27(2,24)25/h3-10,15,18-19,21H,1-2H3,(H,17,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50300454 (CHEMBL574378 | N-hydroxy-2,2-bis(4-(methylsulfonam...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(C(=O)NO)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C16H19N3O6S2/c1-26(22,23)18-13-7-3-11(4-8-13)15(16(20)17-21)12-5-9-14(10-6-12)19-27(2,24)25/h3-10,15,18-19,21H,1-2H3,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50300454 (CHEMBL574378 | N-hydroxy-2,2-bis(4-(methylsulfonam...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(C(=O)NO)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C16H19N3O6S2/c1-26(22,23)18-13-7-3-11(4-8-13)15(16(20)17-21)12-5-9-14(10-6-12)19-27(2,24)25/h3-10,15,18-19,21H,1-2H3,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair