null

SMILES: CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N

InChI Key: InChIKey=UTTOGXNQLFEWEI-CIAFOILYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50300670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of human SERT				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of human 5HT2C receptor				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5HT-stimulated cAMP production after 30 mins by HTRF ...				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50300670 ((+/-)-2-(6-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5...) Show SMILES CC1Cc2ccc(NS(=O)(=O)c3c(Cl)nc4sccn34)cc2\C1=N\NC(N)=N Show InChI InChI=1S/C16H16ClN7O2S2/c1-8-6-9-2-3-10(7-11(9)12(8)21-22-15(18)19)23-28(25,26)14-13(17)20-16-24(14)4-5-27-16/h2-5,7-8,23H,6H2,1H3,(H4,18,19,22)/b21-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of human 5HT1A receptor				J Med Chem 52: 6153-7 (2009) Article DOI: 10.1021/jm900796p BindingDB Entry DOI: 10.7270/Q2BG2P3X
					More data for this Ligand-Target Pair