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BDBM50300675 2-(1-(5-(phenylsulfonamido)-1H-indol-3-yl)ethylidene)hydrazinecarboximidamide::CHEMBL573982

SMILES: CC(=NN=C(N)N)c1c[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc12

InChI Key: InChIKey=WANVPEYYQBHQTO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300675   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50300675
PNG
(2-(1-(5-(phenylsulfonamido)-1H-indol-3-yl)ethylide...)
Show SMILES CC(=NN=C(N)N)c1c[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc12 |w:2.2,(28.57,2.48,;29.6,1.34,;31.11,1.66,;31.59,3.12,;33.09,3.44,;33.57,4.91,;34.12,2.3,;29.13,-.13,;30.04,-1.38,;29.13,-2.64,;27.66,-2.16,;26.32,-2.93,;24.99,-2.16,;24.99,-.62,;23.66,.15,;23.65,1.69,;23.64,3.23,;24.97,1.68,;22.11,1.7,;21.36,3.04,;19.82,3.05,;19.04,1.72,;19.81,.38,;21.35,.38,;26.31,.15,;27.65,-.61,)|
Show InChI InChI=1S/C17H18N6O2S/c1-11(21-22-17(18)19)15-10-20-16-8-7-12(9-14(15)16)23-26(24,25)13-5-3-2-4-6-13/h2-10,20,23H,1H3,(H4,18,19,22)
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Article
PubMed
 1n/an/an/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells

J Med Chem 52: 6153-7 (2009)


Article DOI: 10.1021/jm900796p
BindingDB Entry DOI: 10.7270/Q2BG2P3X
More data for this
Ligand-Target Pair