BDBM50300948 (R)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL569492

SMILES: CCCOCCn1c2cc(ncc2nc(N[C@H](C)CO)c1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=MHPIHGUNGZVBEV-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 6A (Homo sapiens (Human))	BDBM50300948 ((R)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...) Show SMILES CCCOCCn1c2cc(ncc2nc(N[C@H](C)CO)c1=O)-c1ccc(OC)nc1 |r| Show InChI InChI=1S/C21H27N5O4/c1-4-8-30-9-7-26-18-10-16(15-5-6-19(29-3)23-11-15)22-12-17(18)25-20(21(26)28)24-14(2)13-27/h5-6,10-12,14,27H,4,7-9,13H2,1-3H3,(H,24,25)/t14-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE6				Bioorg Med Chem Lett 19: 5209-13 (2009) Article DOI: 10.1016/j.bmcl.2009.07.019 BindingDB Entry DOI: 10.7270/Q2H41RHV
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50300948 ((R)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...) Show SMILES CCCOCCn1c2cc(ncc2nc(N[C@H](C)CO)c1=O)-c1ccc(OC)nc1 |r| Show InChI InChI=1S/C21H27N5O4/c1-4-8-30-9-7-26-18-10-16(15-5-6-19(29-3)23-11-15)22-12-17(18)25-20(21(26)28)24-14(2)13-27/h5-6,10-12,14,27H,4,7-9,13H2,1-3H3,(H,24,25)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 19: 5209-13 (2009) Article DOI: 10.1016/j.bmcl.2009.07.019 BindingDB Entry DOI: 10.7270/Q2H41RHV
					More data for this Ligand-Target Pair