BDBM50301004 (+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol::CHEMBL567467

SMILES: CNC[C@H](O)[C@H](c1ccccc1)n1ccc2cc(Cl)ccc12

InChI Key: InChIKey=IPBRKYZIBYMQNY-ROUUACIJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50301004 ((+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methy...) Show SMILES CNC[C@H](O)[C@H](c1ccccc1)n1ccc2cc(Cl)ccc12 |r| Show InChI InChI=1S/C18H19ClN2O/c1-20-12-17(22)18(13-5-3-2-4-6-13)21-10-9-14-11-15(19)7-8-16(14)21/h2-11,17-18,20,22H,12H2,1H3/t17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of seratonin uptake at human SERT expressed in JAR cells				Bioorg Med Chem Lett 19: 5029-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.053 BindingDB Entry DOI: 10.7270/Q2CC10SH
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50301004 ((+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methy...) Show SMILES CNC[C@H](O)[C@H](c1ccccc1)n1ccc2cc(Cl)ccc12 |r| Show InChI InChI=1S/C18H19ClN2O/c1-20-12-17(22)18(13-5-3-2-4-6-13)21-10-9-14-11-15(19)7-8-16(14)21/h2-11,17-18,20,22H,12H2,1H3/t17-,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 5029-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.053 BindingDB Entry DOI: 10.7270/Q2CC10SH
					More data for this Ligand-Target Pair