BDBM50301009 4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpholinomethyl)pyridin-2-yl)quinoline-3-carbonitrile::CHEMBL584915

SMILES: COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCOCC3)cn2)C#N)c(Cl)cc1Cl

InChI Key: InChIKey=RSLHSUVMGKXAEL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50301009 (4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCOCC3)cn2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H23Cl2N5O2/c1-35-26-12-25(21(28)11-22(26)29)33-27-19(13-30)15-32-24-10-18(3-4-20(24)27)23-5-2-17(14-31-23)16-34-6-8-36-9-7-34/h2-5,10-12,14-15H,6-9,16H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 days				Bioorg Med Chem Lett 19: 5071-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.043 BindingDB Entry DOI: 10.7270/Q27M081R
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50301009 (4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...) Show SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCOCC3)cn2)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H23Cl2N5O2/c1-35-26-12-25(21(28)11-22(26)29)33-27-19(13-30)15-32-24-10-18(3-4-20(24)27)23-5-2-17(14-31-23)16-34-6-8-36-9-7-34/h2-5,10-12,14-15H,6-9,16H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of Src				Bioorg Med Chem Lett 19: 5071-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.043 BindingDB Entry DOI: 10.7270/Q27M081R
					More data for this Ligand-Target Pair