BDBM50301084 4-(4-fluorobenzyloxy)-1-(3-(3-(pyrrolidin-1-yl)propoxy)benzyl)pyridin-2(1H)-one::CHEMBL571830

SMILES: Fc1ccc(COc2ccn(Cc3cccc(OCCCN4CCCC4)c3)c(=O)c2)cc1

InChI Key: InChIKey=GEFGDHCYHBZWCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50301084 (4-(4-fluorobenzyloxy)-1-(3-(3-(pyrrolidin-1-yl)pro...) Show SMILES Fc1ccc(COc2ccn(Cc3cccc(OCCCN4CCCC4)c3)c(=O)c2)cc1 Show InChI InChI=1S/C26H29FN2O3/c27-23-9-7-21(8-10-23)20-32-25-11-15-29(26(30)18-25)19-22-5-3-6-24(17-22)31-16-4-14-28-12-1-2-13-28/h3,5-11,15,17-18H,1-2,4,12-14,16,19-20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 5186-90 (2009) Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG
					More data for this Ligand-Target Pair