new BindingDB logo
myBDB logout

BDBM50301085 4-(4-fluorobenzyloxy)-1-(4-(pyrrolidin-1-ylmethyl)phenyl)pyridin-2(1H)-one::CHEMBL566029

SMILES: Fc1ccc(COc2ccn(-c3ccc(CN4CCCC4)cc3)c(=O)c2)cc1

InChI Key: InChIKey=RXUSHGWGUPCMPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301085   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50301085
PNG
(4-(4-fluorobenzyloxy)-1-(4-(pyrrolidin-1-ylmethyl)...)
Show SMILES Fc1ccc(COc2ccn(-c3ccc(CN4CCCC4)cc3)c(=O)c2)cc1
Show InChI InChI=1S/C23H23FN2O2/c24-20-7-3-19(4-8-20)17-28-22-11-14-26(23(27)15-22)21-9-5-18(6-10-21)16-25-12-1-2-13-25/h3-11,14-15H,1-2,12-13,16-17H2
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR


Bioorg Med Chem Lett 19: 5186-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.023
BindingDB Entry DOI: 10.7270/Q2G44QCG
More data for this
Ligand-Target Pair