BDBM50301088 1-(4-((diethylamino)methyl)phenethyl)-4-(4-fluorobenzyloxy)pyridin-2(1H)-one::CHEMBL569458

SMILES: CCN(CC)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1

InChI Key: InChIKey=PKIADIKSNMXZIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50301088 (1-(4-((diethylamino)methyl)phenethyl)-4-(4-fluorob...) Show SMILES CCN(CC)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1 Show InChI InChI=1S/C25H29FN2O2/c1-3-27(4-2)18-21-7-5-20(6-8-21)13-15-28-16-14-24(17-25(28)29)30-19-22-9-11-23(26)12-10-22/h5-12,14,16-17H,3-4,13,15,18-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 5186-90 (2009) Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG
					More data for this Ligand-Target Pair