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BDBM50301091 4-(4-fluorobenzyloxy)-1-(4-((isobutyl(propyl)amino)methyl)phenethyl)pyridin-2(1H)-one::CHEMBL585879

SMILES: CCCN(CC(C)C)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1

InChI Key: InChIKey=JMLRNWMIXJECGB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301091   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50301091
PNG
(4-(4-fluorobenzyloxy)-1-(4-((isobutyl(propyl)amino...)
Show SMILES CCCN(CC(C)C)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1
Show InChI InChI=1S/C28H35FN2O2/c1-4-15-30(19-22(2)3)20-24-7-5-23(6-8-24)13-16-31-17-14-27(18-28(31)32)33-21-25-9-11-26(29)12-10-25/h5-12,14,17-18,22H,4,13,15-16,19-21H2,1-3H3
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.90n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR


Bioorg Med Chem Lett 19: 5186-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.023
BindingDB Entry DOI: 10.7270/Q2G44QCG
More data for this
Ligand-Target Pair