Found 12 hits for monomerid = 50301095 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of delta-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]MCH from human recombinant MCH1R expressed on CHOK1 cell membrane |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human ERG potassium channel 1 |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of mu-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of muscarinic M1 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H1 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H2 Receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H2 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H3 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H4 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of adenosine receptor A2A |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50301095
(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)Show InChI InChI=1S/C24H27FN2O2/c1-2-13-26-17-20-5-3-19(4-6-20)11-14-27-15-12-23(16-24(27)28)29-18-21-7-9-22(25)10-8-21/h3-10,12,15-16,26H,2,11,13-14,17-18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of kappa-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |