Found 3 hits for monomerid = 50301101 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50301101
((2S,3S)-N-hydroxy-5-(2-oxo-2-(pyrrolidin-1-yl)ethy...)Show SMILES ONC(=O)[C@H]1CC(CC(=O)N2CCCC2)CN[C@@H]1C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C23H32N4O4/c28-20(26-9-4-5-10-26)13-16-12-19(22(29)25-31)21(24-14-16)23(30)27-11-8-18(15-27)17-6-2-1-3-7-17/h1-3,6-7,16,18-19,21,24,31H,4-5,8-15H2,(H,25,29)/t16?,18-,19-,21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 365 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of MMP-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
(Homo sapiens (Human)) | BDBM50301101
((2S,3S)-N-hydroxy-5-(2-oxo-2-(pyrrolidin-1-yl)ethy...)Show SMILES ONC(=O)[C@H]1CC(CC(=O)N2CCCC2)CN[C@@H]1C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C23H32N4O4/c28-20(26-9-4-5-10-26)13-16-12-19(22(29)25-31)21(24-14-16)23(30)27-11-8-18(15-27)17-6-2-1-3-7-17/h1-3,6-7,16,18-19,21,24,31H,4-5,8-15H2,(H,25,29)/t16?,18-,19-,21-/m0/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of ADAM-10 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50301101
((2S,3S)-N-hydroxy-5-(2-oxo-2-(pyrrolidin-1-yl)ethy...)Show SMILES ONC(=O)[C@H]1CC(CC(=O)N2CCCC2)CN[C@@H]1C(=O)N1CC[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C23H32N4O4/c28-20(26-9-4-5-10-26)13-16-12-19(22(29)25-31)21(24-14-16)23(30)27-11-8-18(15-27)17-6-2-1-3-7-17/h1-3,6-7,16,18-19,21,24,31H,4-5,8-15H2,(H,25,29)/t16?,18-,19-,21-/m0/s1 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Incyte Corporation
Curated by ChEMBL
| Assay Description Inhibition of HER-2 |
Bioorg Med Chem Lett 19: 5037-42 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.052 BindingDB Entry DOI: 10.7270/Q2154J0S |
More data for this Ligand-Target Pair | |