BDBM50301158 4-(3-methylpyridin-2-yl)-5-(1,5-naphthyridin-2-yl)thiazol-2-amine::CHEMBL576062

SMILES: Cc1cccnc1-c1nc(N)sc1-c1ccc2ncccc2n1

InChI Key: InChIKey=MVQGJLBAZRVGDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50301158 (4-(3-methylpyridin-2-yl)-5-(1,5-naphthyridin-2-yl)...) Show SMILES Cc1cccnc1-c1nc(N)sc1-c1ccc2ncccc2n1 Show InChI InChI=1S/C17H13N5S/c1-10-4-2-9-20-14(10)15-16(23-17(18)22-15)13-7-6-11-12(21-13)5-3-8-19-11/h2-9H,1H3,(H2,18,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair