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SMILES: Cc1cccc(n1)-c1nc(NCc2ccc(cc2)C#N)[nH]c1C1=CC=C2OCOC2C1

InChI Key: InChIKey=MOFJZPPCEKEFEN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301160   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50301160
PNG
(4-((4-(3a,4-dihydrobenzo[d][1,3]dioxol-5-yl)-5-(6-...)
Show SMILES Cc1cccc(n1)-c1nc(NCc2ccc(cc2)C#N)[nH]c1C1=CC=C2OCOC2C1 |t:25,27|
Show InChI InChI=1S/C24H21N5O2/c1-15-3-2-4-19(27-15)23-22(18-9-10-20-21(11-18)31-14-30-20)28-24(29-23)26-13-17-7-5-16(12-25)6-8-17/h2-10,21H,11,13-14H2,1H3,(H2,26,28,29)
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of TGFR1

Eur J Med Chem 44: 4259-65 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.008
BindingDB Entry DOI: 10.7270/Q2BC3ZM9
More data for this
Ligand-Target Pair