BDBM50301167 CHEMBL567706::N,N-dimethyl-3-(3-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)phenyl)propan-1-amine

SMILES: CN(C)CCCc1cccc(c1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key: InChIKey=SWEOHBUPPVVRBO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50301167 (CHEMBL567706 | N,N-dimethyl-3-(3-(4-(3-(pyridin-2-...) Show SMILES CN(C)CCCc1cccc(c1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C24H25N5/c1-29(2)14-6-8-18-7-5-9-20(15-18)23-16-19(11-13-26-23)21-17-27-28-24(21)22-10-3-4-12-25-22/h3-5,7,9-13,15-17H,6,8,14H2,1-2H3,(H,27,28)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair