BDBM50301171 5-(8-methylquinolin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine::CHEMBL565643

SMILES: Cc1cccc2ccc(nc12)-c1sc(N)nc1-c1ccccn1

InChI Key: InChIKey=GPZVVGLZONKKIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50301171 (5-(8-methylquinolin-2-yl)-4-(pyridin-2-yl)thiazol-...) Show SMILES Cc1cccc2ccc(nc12)-c1sc(N)nc1-c1ccccn1 Show InChI InChI=1S/C18H14N4S/c1-11-5-4-6-12-8-9-14(21-15(11)12)17-16(22-18(19)23-17)13-7-2-3-10-20-13/h2-10H,1H3,(H2,19,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair