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BDBM50301334 5-chloro-6-(4-(3-((4-chlorophenyl)(methyl)amino)propyl)piperazin-1-yl)-N-(2-phenoxyethyl)nicotinamide::CHEMBL569336

SMILES: CN(CCCN1CCN(CC1)c1ncc(cc1Cl)C(=O)NCCOc1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=BSMNBHPERYKHAU-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301334   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
chemokine (C-X-C motif) receptor 3


(Homo sapiens (Human))		BDBM50301334
PNG
(5-chloro-6-(4-(3-((4-chlorophenyl)(methyl)amino)pr...)
Show SMILES CN(CCCN1CCN(CC1)c1ncc(cc1Cl)C(=O)NCCOc1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H33Cl2N5O2/c1-33(24-10-8-23(29)9-11-24)13-5-14-34-15-17-35(18-16-34)27-26(30)20-22(21-32-27)28(36)31-12-19-37-25-6-3-2-4-7-25/h2-4,6-11,20-21H,5,12-19H2,1H3,(H,31,36)
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Similars
Article
PubMed
 2.00E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation counting

Bioorg Med Chem Lett 19: 5205-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.020
BindingDB Entry DOI: 10.7270/Q21V5F18
More data for this
Ligand-Target Pair