BDBM50301336 6-(4-(1-benzylpiperidin-4-yl)piperazin-1-yl)-5-chloro-N-(2-phenoxyethyl)nicotinamide::CHEMBL565559
SMILES: Clc1cc(cnc1N1CCN(CC1)C1CCN(Cc2ccccc2)CC1)C(=O)NCCOc1ccccc1
InChI Key: InChIKey=VKQDVVFNDNSOHJ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human)) | BDBM50301336 (6-(4-(1-benzylpiperidin-4-yl)piperazin-1-yl)-5-chl...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation counting | Bioorg Med Chem Lett 19: 5205-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.020 BindingDB Entry DOI: 10.7270/Q21V5F18 | |||||||||||
More data for this Ligand-Target Pair |