BindingDB logo
myBDB logout

null

SMILES: OC1c2cccc(C#N)c2C=Cc2ncc(cc12)-c1ccccc1

InChI Key: InChIKey=OXFOFNYOKZJKMZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301369   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50301369
PNG
((+)--5-Hydroxy-3-phenyl-5H-benzo[4,5]cyclohepta[1,...)
Show SMILES OC1c2cccc(C#N)c2C=Cc2ncc(cc12)-c1ccccc1 |c:11|
Show InChI InChI=1S/C21H14N2O/c22-12-15-7-4-8-18-17(15)9-10-20-19(21(18)24)11-16(13-23-20)14-5-2-1-3-6-14/h1-11,13,21,24H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Antagonistic activity against NR2B receptor expressed in mouse Ltk cells assessed as inhibition of calcium influx by FLIPR assay

Bioorg Med Chem Lett 19: 5132-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.028
BindingDB Entry DOI: 10.7270/Q2X34XJW
More data for this
Ligand-Target Pair