BDBM50301396 CHEMBL572034::Phenyl-[1-(4-p-tolyl-butyl)-piperidin-4-yl]-methanol
SMILES: Cc1ccc(CCCCN2CCC(CC2)C(O)c2ccccc2)cc1
InChI Key: InChIKey=RGGWURWNJUDTIH-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50301396 (CHEMBL572034 | Phenyl-[1-(4-p-tolyl-butyl)-piperid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 121 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by betaplate scintillation counting | Bioorg Med Chem Lett 19: 5043-7 (2009) Article DOI: 10.1016/j.bmcl.2009.07.047 BindingDB Entry DOI: 10.7270/Q2NP24HJ | |||||||||||
More data for this Ligand-Target Pair |