BDBM50301532 4-fluoro-N-methyl-N-(4-(pyridin-2-yl)thiazol-2-yl)benzamide::CHEMBL572135

SMILES: CN(C(=O)c1ccc(F)cc1)c1nc(cs1)-c1ccccn1

InChI Key: InChIKey=HMEPCQJITOKZCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50301532 (4-fluoro-N-methyl-N-(4-(pyridin-2-yl)thiazol-2-yl)...) Show SMILES CN(C(=O)c1ccc(F)cc1)c1nc(cs1)-c1ccccn1 Show InChI InChI=1S/C16H12FN3OS/c1-20(15(21)11-5-7-12(17)8-6-11)16-19-14(10-22-16)13-4-2-3-9-18-13/h2-10H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 receptor expressed in CHO cells by FLIPR assay				Bioorg Med Chem Lett 19: 5464-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.097 BindingDB Entry DOI: 10.7270/Q2W66KTT
					More data for this Ligand-Target Pair