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SMILES: CN(C(=O)c1ccc(F)cc1)c1nc(cs1)-c1cnccn1

InChI Key: InChIKey=CNLCCQIYHWYAQX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301533   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))		BDBM50301533
PNG
(4-fluoro-N-methyl-N-(4-(pyrazin-2-yl)thiazol-2-yl)...)
Show SMILES CN(C(=O)c1ccc(F)cc1)c1nc(cs1)-c1cnccn1
Show InChI InChI=1S/C15H11FN4OS/c1-20(14(21)10-2-4-11(16)5-3-10)15-19-13(9-22-15)12-8-17-6-7-18-12/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 49n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1 receptor expressed in CHO cells by FLIPR assay

Bioorg Med Chem Lett 19: 5464-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.097
BindingDB Entry DOI: 10.7270/Q2W66KTT
More data for this
Ligand-Target Pair