BDBM50301676 5-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL567930

SMILES: CN(C)Cc1cccc(c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C

InChI Key: InChIKey=GQDKNFXTRUBAEB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50301676 (5-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...) Show SMILES CN(C)Cc1cccc(c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C24H23N5/c1-16-20-9-10-27-23(20)8-7-22(16)28-24-19(12-25)13-26-14-21(24)18-6-4-5-17(11-18)15-29(2)3/h4-11,13-14,27H,15H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50301676 (5-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...) Show SMILES CN(C)Cc1cccc(c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C24H23N5/c1-16-20-9-10-27-23(20)8-7-22(16)28-24-19(12-25)13-26-14-21(24)18-6-4-5-17(11-18)15-29(2)3/h4-11,13-14,27H,15H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair