BDBM50301677 5-(2-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL566868
SMILES: CN(C)Cc1ccccc1-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
InChI Key: InChIKey=PFLNTCJFHFSURE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50301677 (5-(2-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human PKCdelta by IMAP kinase assay | Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50301677 (5-(2-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human PKCtheta by IMAP kinase assay | Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF | |||||||||||
More data for this Ligand-Target Pair |