BDBM50301684 4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpiperazin-1-yl)methyl)thiophen-2-yl)nicotinonitrile::CHEMBL567300

SMILES: CN1CCN(Cc2ccc(s2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key: InChIKey=JNXDDALKPXMKQB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50301684 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...) Show SMILES CN1CCN(Cc2ccc(s2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C25H26N6S/c1-17-20-7-8-28-23(20)5-4-22(17)29-25-18(13-26)14-27-15-21(25)24-6-3-19(32-24)16-31-11-9-30(2)10-12-31/h3-8,14-15,28H,9-12,16H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50301684 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...) Show SMILES CN1CCN(Cc2ccc(s2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C25H26N6S/c1-17-20-7-8-28-23(20)5-4-22(17)29-25-18(13-26)14-27-15-21(25)24-6-3-19(32-24)16-31-11-9-30(2)10-12-31/h3-8,14-15,28H,9-12,16H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair