BDBM50301685 1-((4-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl)phenyl)thiophen-2-yl)methyl)-4-methylpiperazine::CHEMBL567082

SMILES: CN1CCN(Cc2cc(cs2)-c2cccc(C#C)c2Cc2ccc3CC=Cc3c2C)CC1

InChI Key: InChIKey=SJLWKRZGICWCDL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50301685 (1-((4-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...) Show SMILES CN1CCN(Cc2cc(cs2)-c2cccc(C#C)c2Cc2ccc3CC=Cc3c2C)CC1 |c:27| Show InChI InChI=1S/C29H30N2S/c1-4-22-7-5-10-28(25-17-26(32-20-25)19-31-15-13-30(3)14-16-31)29(22)18-24-12-11-23-8-6-9-27(23)21(24)2/h1,5-7,9-12,17,20H,8,13-16,18-19H2,2-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50301685 (1-((4-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...) Show SMILES CN1CCN(Cc2cc(cs2)-c2cccc(C#C)c2Cc2ccc3CC=Cc3c2C)CC1 |c:27| Show InChI InChI=1S/C29H30N2S/c1-4-22-7-5-10-28(25-17-26(32-20-25)19-31-15-13-30(3)14-16-31)29(22)18-24-12-11-23-8-6-9-27(23)21(24)2/h1,5-7,9-12,17,20H,8,13-16,18-19H2,2-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair