BDBM50301689 4-(4-methyl-1H-indol-5-ylamino)-5-(5-(thiomorpholinomethyl)furan-2-yl)nicotinonitrile::CHEMBL585323
SMILES: Cc1c(Nc2c(cncc2-c2ccc(CN3CCSCC3)o2)C#N)ccc2[nH]ccc12
InChI Key: InChIKey=JTUGJZFQRMCZQW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50301689 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM50301689
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(thiomorpholi...)Show SMILES Cc1c(Nc2c(cncc2-c2ccc(CN3CCSCC3)o2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-16-19-6-7-27-22(19)4-3-21(16)28-24-17(12-25)13-26-14-20(24)23-5-2-18(30-23)15-29-8-10-31-11-9-29/h2-7,13-14,27H,8-11,15H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human PKCdelta by IMAP kinase assay |
Bioorg Med Chem Lett 19: 5423-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.109
BindingDB Entry DOI: 10.7270/Q2V69JPF |
More data for this
Ligand-Target Pair | |
Protein kinase C theta type
(Homo sapiens (Human)) | BDBM50301689
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(thiomorpholi...)Show SMILES Cc1c(Nc2c(cncc2-c2ccc(CN3CCSCC3)o2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-16-19-6-7-27-22(19)4-3-21(16)28-24-17(12-25)13-26-14-20(24)23-5-2-18(30-23)15-29-8-10-31-11-9-29/h2-7,13-14,27H,8-11,15H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human PKCtheta by IMAP kinase assay |
Bioorg Med Chem Lett 19: 5423-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.109
BindingDB Entry DOI: 10.7270/Q2V69JPF |
More data for this
Ligand-Target Pair | |
Search and Browse
