BDBM50301738 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-isopropyl-5-methyl-1H-imidazol-4-yl)-4-methyl-1H-pyrazole::CHEMBL577040

SMILES: CC(C)n1cnc(c1C)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=PNYJPKICYAHOOO-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50301738 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...) Show SMILES CC(C)n1cnc(c1C)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H21Cl3N4/c1-13(2)29-12-27-22(15(29)4)21-14(3)23(16-5-7-17(24)8-6-16)30(28-21)20-10-9-18(25)11-19(20)26/h5-13H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor				Bioorg Med Chem Lett 19: 5351-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.130 BindingDB Entry DOI: 10.7270/Q2KP827S
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50301738 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...) Show SMILES CC(C)n1cnc(c1C)-c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H21Cl3N4/c1-13(2)29-12-27-22(15(29)4)21-14(3)23(16-5-7-17(24)8-6-16)30(28-21)20-10-9-18(25)11-19(20)26/h5-13H,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assay				Bioorg Med Chem Lett 19: 5351-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.130 BindingDB Entry DOI: 10.7270/Q2KP827S
					More data for this Ligand-Target Pair