null
SMILES: C[C@@H]1CNCCN1c1cc(=O)n(C)c(COc2ccccc2C(F)(F)F)n1
InChI Key: InChIKey=XIFVRPRCVBESLU-GFCCVEGCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.50E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2A receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair |