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SMILES: Cc1cc(=O)n(CCCOc2ccccc2)c(n1)N1CCNCC1

InChI Key: InChIKey=MCJDAUSDPHMHLQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301773   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50301773
PNG
(6-methyl-3-(3-phenoxypropyl)-2-(piperazin-1-yl)pyr...)
Show SMILES Cc1cc(=O)n(CCCOc2ccccc2)c(n1)N1CCNCC1
Show InChI InChI=1S/C18H24N4O2/c1-15-14-17(23)22(18(20-15)21-11-8-19-9-12-21)10-5-13-24-16-6-3-2-4-7-16/h2-4,6-7,14,19H,5,8-13H2,1H3
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Similars
Article
PubMed
n/an/an/an/a 1.02E+3n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay

Bioorg Med Chem Lett 19: 5346-50 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.133
BindingDB Entry DOI: 10.7270/Q2B56JT3
More data for this
Ligand-Target Pair