BDBM50301856 7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-amine::CHEMBL577695

SMILES: FC(F)(F)c1ccc(Nc2noc3c(cccc23)C(F)(F)F)cc1

InChI Key: InChIKey=RPRBCFLRKRZGKQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50301856 (7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...) Show SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C15H8F6N2O/c16-14(17,18)8-4-6-9(7-5-8)22-13-10-2-1-3-11(15(19,20)21)12(10)24-23-13/h1-7H,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human sEH				Bioorg Med Chem Lett 19: 5716-21 (2009) Article DOI: 10.1016/j.bmcl.2009.08.006 BindingDB Entry DOI: 10.7270/Q2Z0388B
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50301856 (7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...) Show SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C15H8F6N2O/c16-14(17,18)8-4-6-9(7-5-8)22-13-10-2-1-3-11(15(19,20)21)12(10)24-23-13/h1-7H,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human sEH assessed as DHET production in presence of 10% human serum				Bioorg Med Chem Lett 19: 5716-21 (2009) Article DOI: 10.1016/j.bmcl.2009.08.006 BindingDB Entry DOI: 10.7270/Q2Z0388B
					More data for this Ligand-Target Pair
Epoxide hydrolase 2 (Rattus norvegicus)	BDBM50301856 (7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...) Show SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C15H8F6N2O/c16-14(17,18)8-4-6-9(7-5-8)22-13-10-2-1-3-11(15(19,20)21)12(10)24-23-13/h1-7H,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat sEH				Bioorg Med Chem Lett 19: 5716-21 (2009) Article DOI: 10.1016/j.bmcl.2009.08.006 BindingDB Entry DOI: 10.7270/Q2Z0388B
					More data for this Ligand-Target Pair