BDBM50301869 7-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-amine::CHEMBL578548

SMILES: FC(F)(F)c1ccc(Nc2noc3c(cccc23)-c2ccccc2C(F)(F)F)cc1

InChI Key: InChIKey=GHMMGNGURMNRPZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epoxide hydrolase 2 (Rattus norvegicus)	BDBM50301869 (7-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...) Show SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C21H12F6N2O/c22-20(23,24)12-8-10-13(11-9-12)28-19-16-6-3-5-15(18(16)30-29-19)14-4-1-2-7-17(14)21(25,26)27/h1-11H,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat sEH				Bioorg Med Chem Lett 19: 5716-21 (2009) Article DOI: 10.1016/j.bmcl.2009.08.006 BindingDB Entry DOI: 10.7270/Q2Z0388B
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50301869 (7-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...) Show SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)-c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C21H12F6N2O/c22-20(23,24)12-8-10-13(11-9-12)28-19-16-6-3-5-15(18(16)30-29-19)14-4-1-2-7-17(14)21(25,26)27/h1-11H,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human sEH				Bioorg Med Chem Lett 19: 5716-21 (2009) Article DOI: 10.1016/j.bmcl.2009.08.006 BindingDB Entry DOI: 10.7270/Q2Z0388B
					More data for this Ligand-Target Pair