Found 3 hits for monomerid = 50301954 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50301954
((S)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydr...)Show SMILES CN1C(=O)NC(=O)[C@@]11Cc2ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc2C1 |r| Show InChI InChI=1S/C26H30N4O4/c1-25(2,3)23(33)30(15-17-8-6-5-7-9-17)16-21(31)27-20-11-10-18-13-26(14-19(18)12-20)22(32)28-24(34)29(26)4/h5-12H,13-16H2,1-4H3,(H,27,31)(H,28,32,34)/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 5787-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.134 BindingDB Entry DOI: 10.7270/Q2PG1RTW |
More data for this Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50301954
((S)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydr...)Show SMILES CN1C(=O)NC(=O)[C@@]11Cc2ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc2C1 |r| Show InChI InChI=1S/C26H30N4O4/c1-25(2,3)23(33)30(15-17-8-6-5-7-9-17)16-21(31)27-20-11-10-18-13-26(14-19(18)12-20)22(32)28-24(34)29(26)4/h5-12H,13-16H2,1-4H3,(H,27,31)(H,28,32,34)/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant CGRP receptor |
Bioorg Med Chem Lett 20: 6827-30 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.105 BindingDB Entry DOI: 10.7270/Q2Z89CNJ |
More data for this Ligand-Target Pair | |
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human)) | BDBM50301954
((S)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydr...)Show SMILES CN1C(=O)NC(=O)[C@@]11Cc2ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc2C1 |r| Show InChI InChI=1S/C26H30N4O4/c1-25(2,3)23(33)30(15-17-8-6-5-7-9-17)16-21(31)27-20-11-10-18-13-26(14-19(18)12-20)22(32)28-24(34)29(26)4/h5-12H,13-16H2,1-4H3,(H,27,31)(H,28,32,34)/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cells |
Bioorg Med Chem Lett 19: 5787-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.134 BindingDB Entry DOI: 10.7270/Q2PG1RTW |
More data for this Ligand-Target Pair | |