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BDBM50301955 (+/-)-N-(2-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide::CHEMBL571350

SMILES: CN1C(=O)NC(=O)C11Cc2ccc(NC(=O)CN(Cc3ccccc3F)C(=O)C(C)(C)C)cc2C1

InChI Key: InChIKey=NGFGAGGEIHNIOT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301955   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))		BDBM50301955
PNG
((+/-)-N-(2-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-...)
Show SMILES CN1C(=O)NC(=O)C11Cc2ccc(NC(=O)CN(Cc3ccccc3F)C(=O)C(C)(C)C)cc2C1
Show InChI InChI=1S/C26H29FN4O4/c1-25(2,3)23(34)31(14-17-7-5-6-8-20(17)27)15-21(32)28-19-10-9-16-12-26(13-18(16)11-19)22(33)29-24(35)30(26)4/h5-11H,12-15H2,1-4H3,(H,28,32)(H,29,33,35)
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Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Merck& Co.

Curated by ChEMBL


Assay Description
Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cells

Bioorg Med Chem Lett 19: 5787-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.134
BindingDB Entry DOI: 10.7270/Q2PG1RTW
More data for this
Ligand-Target Pair