BDBM50302037 5-(5-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)methyl)benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL569822

SMILES: CN(C)CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key: InChIKey=HDYPWSDXJZTYPP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302037 (5-(5-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)me...) Show SMILES CN(C)CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C32H35N7O/c1-22-26-8-9-35-29(26)6-5-28(22)36-32-25(18-33)19-34-20-27(32)31-17-24-16-23(4-7-30(24)40-31)21-39-14-12-38(13-15-39)11-10-37(2)3/h4-9,16-17,19-20,35H,10-15,21H2,1-3H3,(H,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302037 (5-(5-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)me...) Show SMILES CN(C)CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C32H35N7O/c1-22-26-8-9-35-29(26)6-5-28(22)36-32-25(18-33)19-34-20-27(32)31-17-24-16-23(4-7-30(24)40-31)21-39-14-12-38(13-15-39)11-10-37(2)3/h4-9,16-17,19-20,35H,10-15,21H2,1-3H3,(H,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair