BDBM50302039 4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(pyridin-2-yl)piperazin-1-yl)methyl)benzofuran-2-yl)nicotinonitrile::CHEMBL571281
SMILES: Cc1c(Nc2c(cncc2-c2cc3cc(CN4CCN(CC4)c4ccccn4)ccc3o2)C#N)ccc2[nH]ccc12
InChI Key: InChIKey=FAQJIZKBJRQPIA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C delta type (Homo sapiens (Human)) | BDBM50302039 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of PKCdelta by IMAP fluorescence polarization technology | Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50302039 (4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human PKCtheta by IMAP fluorescence polarization technology | Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q | |||||||||||
More data for this Ligand-Target Pair |